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Our laboratory program uses a combination of genomics, proteomics, and metabolomics approaches to understand how insects (i) respond to xenobiotic challenges and (ii) evolve resistance to these challenges.  Past and current projects have been performed in collaboration with groups at the University of Illinois at Urbana-Champaign, Harvard University, Carnegie Mellon University, Purdue University, the University of Massachusetts at Amherst, Indiana University-Purdue University at Indianapolis, and the Max Planck Institution for Chemical Ecology.

Past Projects include:

  1. Molecular basis of pesticide resistance
  2. Responses of the digestive system to dietary factors such as lectins (wheat germ agglutinin) 
    and protease inhibitors (Bowman-Birk inhibitors)
  3. “Omics” approaches for use in integrated pest management strategies
  4. Molecular responses to oxidative stressors.

Model Systems include:

  1. Drosophila melanogaster
  2. Human body and head lice
  3. Termites
  4. Cowpea bruchids
  5. The legume pod borer

Selected Publications