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Arthur L Devries

Profile picture for Arthur L Devries

Contact Information

Physiology and Biophysics
524 Burrill Hall
407 S Goodwin
Urbana, IL 61801

Professor Emeritus

Research Description

Role of Glycopeptide and Peptide Antifreezes in Inhibition of Ice Crystal Growth and Recrystallization

Our research program involves studies on the role of antifreeze glycopeptides and peptides (AFGPs and AFPs) in the freezing avoidance of cold-water fishes. Specific aspects are studies of the mechanism of AFGPs and AFPs in inhibiting ice crystal growth and recrystallization, primary and 3-dimensional structures of AFGPs and AFPs to determine structure-function relationships, the physiology of AFGPs and AFPs, and the organization and expression of the antifreeze gene. The use of antifreeze proteins in preventing the growth of large ice crystals (inhibition of recrystallization) in frozen foods, and cryomedial preservation are long term goals.


Ph.D. Stanford University

Additional Campus Affiliations

Professor Emeritus, Evolution, Ecology, and Behavior

Recent Publications

DeVries, A. L. (2024). Identifying Ice-Binding Proteins in Nature. In R. Drori, & C. Stevens (Eds.), Ice Binding Proteins: Methods and Protocols (pp. 3-23). (Methods in Molecular Biology; Vol. 2730). Humana Press Inc..

Schwidetzky, R., de Almeida Ribeiro, I., Bothen, N., Backes, A. T., DeVries, A. L., Bonn, M., Fröhlich-Nowoisky, J., Molinero, V., & Meister, K. (2023). Functional aggregation of cell-free proteins enables fungal ice nucleation. Proceedings of the National Academy of Sciences, 120(46), Article e2303243120.

Sun, Y., Maltseva, D., Liu, J., Hooker, T., Mailänder, V., Ramløv, H., Devries, A. L., Bonn, M., & Meister, K. (2022). Ice Recrystallization Inhibition Is Insufficient to Explain Cryopreservation Abilities of Antifreeze Proteins. Biomacromolecules, 23(3), 1214-1220.

Sun, Y., Giubertoni, G., Bakker, H. J., Liu, J., Wagner, M., Ng, D. Y. W., Devries, A. L., & Meister, K. (2021). Disaccharide Residues are Required for Native Antifreeze Glycoprotein Activity. Biomacromolecules, 22(6), 2595-2603.

Devries, A. L. (2020). Fish antifreeze proteins. In Antifreeze Proteins Volume 1: Environment, Systematics and Evolution (pp. 85-129). Springer.

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